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Ortho Biotech Inc
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Image Search Results
Journal:
Article Title: Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury
doi: 10.1073/pnas.042693799
Figure Lengend Snippet: EPO administered at the time of spinal cord reperfusion is associated with a significant improvement in the neurological score within 1 h after reperfusion. Whereas saline treated animals did not significantly improve over the following 48 h, rHu-EPO treated animals improved further compared with the neurological score obtained in the immediate postoperative period. *, P < 0.05
Article Snippet: Treatment groups received
Techniques:
Journal:
Article Title: Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury
doi: 10.1073/pnas.042693799
Figure Lengend Snippet: Histopathological scoring of spinal cord tissue sections shows that rHu-EPO treatment is associated with markedly reduced cellular injury when compared with saline-treated animals. Based on this pathological analysis, 800 units/kg bw rHu-EPO appeared to protect better than the other two dosages of rHu-EPO tested, despite similar neurological scores.
Article Snippet: Treatment groups received
Techniques:
Journal:
Article Title: Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury
doi: 10.1073/pnas.042693799
Figure Lengend Snippet: Saline-treated animals exhibit TUNEL-positive motor neurons (Left) in contrast to TUNEL-negative sections after rHu-EPO treatment (Right). White matter was devoid of TUNEL-positive cells (not shown). (Scale bar = 80 μm.)
Article Snippet: Treatment groups received
Techniques: TUNEL Assay
Journal: Self Nonself
Article Title: Immunogenicity of protein therapeutics
doi: 10.4161/self.1.4.13904
Figure Lengend Snippet: FDA approved (b) other biologics (adapted from http://www.fda.gov/BiologicsBloodVaccines/ucm133705.htm ) showing the level of reported immunogenicity observed in patients from prescribing information available at http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm
Article Snippet: Preventing infection in cancer 3% Retavase PDL Biopharma rHu TPA Myocardial infarction, pulmonary embolism 0% (2400) Humatrope Eli Lilly rHu Growth hormone Dwarfism 1.6% Adagen Enzon Pharmaceuticals Bovine ADA Adenosine deaminase Inherited immunodeficiency Not reported (
Techniques: Coagulation, Infection